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Head-to-head verdict

Synergy Rx vs ShedRx

Two GLP-1 providers, ruled side by side on The Verdict Score — our published six-factor rubric. Same yardstick, and no score is adjusted for payment.

Grade C · #34

Synergy Rx

Will prescribe brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock access to its clinical team.

Visit Synergy Rx
vs
WinnerGrade B+ · #5

ShedRx

The widest formulary on this board — injections, drops, lozenges and an oral pill, plus real brand Zepbound — with health coaching bundled in.

Visit ShedRx

The verdict

Winner: ShedRx

ShedRx takes it with a higher Verdict Score — 87/100 to 79/100 (grade B+ vs C). People who want options rather than one route: a needle-free form, a brand pathway, or coaching included instead of sold separately. Synergy Rx still earns its place — people who specifically want a brand-name path and as much clinician contact as they can get, and who will accept getting pricing by enquiry.

Neither of these is our overall #1. That title goes to CoreAge Rx (94/100) — the most honest middle of the market: nationwide access, both molecules at one flat, no-surprise price.

Factor by factor

Both scored on the same six factors — see the methodology. The brass bar marks the stronger side on each.

76Real-world results86
58Price honesty86
92Prescriber access83
90Formulary choice90
70Cancellation fairness88
90Member support88

Price, coverage & features

MetricSynergy RxShedRx
Verdict Score79/10087/100
GradeCB+
SemaglutideFrom $199/mo$199/mo
TirzepatideFrom $349/mo$299/mo
CoverageNot disclosedAll 50 states
Brand-name accessYesYes
Oral / sublingualNoYes

Synergy Rx

What we like

  • Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate — rare on this board
  • Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
  • A $100 welcome credit applied at checkout, and FSA/HSA eligible

The caveats

  • Publishes no GLP-1 price anywhere on its own site — it prices its longevity line openly and the medication this page is about not at all
  • At $349/mo, tirzepatide sits roughly $100 above the compounded median we track
  • Does not publish which states it serves
  • No published cancellation or refund terms

ShedRx

What we like

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and an oral daily pill — plus brand Zepbound and Wegovy
  • Tirzepatide $299/mo month-to-month falling to $239 on a twelve-month plan; semaglutide $199 falling to $159
  • Health coaching included with membership rather than upsold
  • Publishes a 120-day weight-loss guarantee, which almost nothing else here offers

The caveats

  • The advertised "as low as $239" tirzepatide rate requires committing to twelve months — month-to-month is $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
  • The dispensing compounding pharmacy is not publicly named

Also worth a look

People who specifically want a brand-name path and as much clinician contact as they can get, and who will accept getting pricing by enquiry.

Visit Synergy Rx Read the full Synergy Rx review →

Our pick — visit

People who want options rather than one route: a needle-free form, a brand pathway, or coaching included instead of sold separately.

Visit ShedRx Read the full ShedRx review →

Keep comparing

Or browse the full comparison hub and the complete rankings.

Pricing, states and verification reflect each provider's public disclosures at last review; the Verdict Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.