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Head-to-head verdict

Enhance MD vs Vaylen

Two GLP-1 providers, ruled side by side on The Verdict Score — our published six-factor rubric. Same yardstick, no pay-to-win placement.

Grade B · #20

Enhance MD

Earns its keep on pricing transparency — every tier is published, dose-flat and includes combo and microdose options — but the verdict holds it back for a compounded-only formulary and a state map it won't show.

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vs
WinnerGrade B+ · #5

Vaylen

The widest formulary on the board — both molecules, brand-name and oral routes — nationwide and LegitScript-verified.

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The verdict

Winner: Vaylen

Vaylen takes it with a higher Verdict Score — 88/100 to 85/100 (grade B+ vs B). Anyone who wants every option on one account: compounded, brand-name or oral, without leaving to shop around. Enhance MD still earns its place — shoppers who value knowing the exact price of every dose and combo up front, and who want lab testing folded into the program.

Neither of these is our overall #1. That title goes to CoreAge Rx (94/100) — the most honest middle of the market: nationwide access, both molecules at one flat, no-surprise price.

Factor by factor

Both scored on the same six factors — see the methodology. The brass bar marks the stronger side on each.

84Real-world results86
88Price honesty87
82Prescriber access90
86Formulary choice91
84Cancellation fairness86
86Member support86

Price, coverage & features

MetricEnhance MDVaylen
Verdict Score85/10088/100
GradeBB+
Semaglutide$212/mo$179/mo
Tirzepatide$280/mo$239/mo
CoverageNot publicly listedAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualNoYes

Enhance MD

What we like

  • Fully transparent tiered pricing: compounded semaglutide $212/mo, tirzepatide $280/mo, microdose $169/mo and a sema/tirz combo at $322/mo
  • Dose-flat pricing — the sticker doesn't climb as you titrate up
  • Metabolic lab testing every 6 months plus real provider support built into the plan
  • NAD+ available for patients pursuing metabolic and longevity goals alongside the GLP-1

The caveats

  • Every GLP-1 here is compounded, not FDA-approved — no brand-name fallback
  • No oral or sublingual route
  • States served are not publicly listed, so you can't confirm coverage before signing up
  • Higher entry price than the flat-rate discounters on this board (first month runs $112, then $212)

Vaylen

What we like

  • Full formulary: both molecules plus brand-name and oral routes
  • LegitScript-certified and available in all 50 states
  • Fair mid-market pricing for the breadth on offer

The caveats

  • Not the cheapest per molecule
  • Younger brand without a long outcomes record

Also worth a look

Shoppers who value knowing the exact price of every dose and combo up front, and who want lab testing folded into the program.

Visit Enhance MD Read the full Enhance MD review →

Our pick — visit

Anyone who wants every option on one account: compounded, brand-name or oral, without leaving to shop around.

Visit Vaylen Read the full Vaylen review →

Keep comparing

Or browse the full comparison hub and the complete rankings.

Pricing, states and verification reflect each provider's public disclosures at last review; the Verdict Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.