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The alternatives

The best alternatives to Signos

Signos scores 68/100 (grade C, ranked #222) on The Verdict Score. Here are the top-rated GLP-1 providers we'd weigh against it — same six-factor rubric, and no score is adjusted for payment.

Read our full Signos review →

Grade C

Rex MD

Rex MD is a US-based men's-health telehealth platform (a LifeMD brand) offering a 100 percent online GLP-1 weight-management program.

Rex MD matches Signos at 68/100; our Rex MD ruling in full has the pricing conditions and the caveats in detail.

Sema
From $199/mo (brand-name)
Tirz
From $349/mo (brand Zepbound)
Coverage
All 50 states
Grade C

Society of You

Society of You is a US telehealth brand (Society Management Group) offering compounded GLP-1 weight-loss medication filled through named partner pharmacies (Emerald and Striker).

Society of You matches Signos at 68/100; the full Society of You review has the pricing conditions and the caveats in detail.

Sema
From $279/mo (promotional rate, compounded)
Tirz
From $425/mo (compounded)
Coverage
Not disclosed
Grade C

Regenics

Regenics is a hybrid in-office and telemedicine health-optimization clinic based in Tarzana, CA, pairing compounded GLP-1 weight loss with TRT, blood panels, IV infusions, aesthetics, and more — patients…

Regenics matches Signos at 68/100; our Regenics ruling in full has the pricing conditions and the caveats in detail.

Sema
From $199/mo (starting dose, compounded)
Tirz
From $279/mo (starting dose, compounded)
Coverage
Not disclosed
Grade C

Velvet Rx

Velvet Rx (velvetrx.com) is a cash-pay telehealth platform offering compounded semaglutide, compounded tirzepatide, and an oral GLP-1 across three publicly-listed SKUs ranging from $139 to $199 'today'…

Velvet Rx matches Signos at 68/100; our Velvet Rx ruling in full has the pricing conditions and the caveats in detail.

Sema
From $299/mo (compounded)
Tirz
From $359/mo (compounded)
Coverage
Not disclosed
Grade C

Options Medical Weight Loss

Options Medical Weight Loss offers telehealth medical weight-loss programs built around compounded GLP-1 — semaglutide starting around $239/month and tirzepatide from $299/month, plus NAD+ injections at…

Options Medical Weight Loss matches Signos at 68/100; our Options Medical Weight Loss ruling in full has the pricing conditions and the caveats in detail.

Sema
From $199/mo (compounded)
Tirz
From $399/mo (compounded)
Coverage
Not disclosed
Grade C

Willow

Telehealth provider offering compounded GLP-1 medications in both tablet and injectable formats.

Willow matches Signos at 68/100; the full Willow review has the pricing conditions and the caveats in detail.

Sema
From $299/mo (starting dose, compounded)
Tirz
From $399/mo (starting dose, compounded)
Coverage
Not disclosed

See the complete rankings or head to the comparison hub.

Pricing, states and verification reflect each provider's public disclosures at last review; the Verdict Score is our editorial judgment per the methodology. Not medical advice; see our disclosure.