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Ranked #279 · Grade C

Lyfe Rx review

By Alyssa Selinger, Editor

Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).

Lyfe Rx — FDA warning letter, September 2025. Addressed to Lyfe Rx, and public in FDA’s warning-letter database.

  • SemaglutideFrom $225/mo
  • TirzepatideFrom $299/mo
Visit Lyfe Rx

Assume we may earn a commission, at no cost to you. Partners we work with carry a small, fixed edge in where they are listed; the scores themselves are not adjusted.

Semaglutide
From $225/mo (compounded)
Tirzepatide
From $299/mo (compounded)
Coverage
Not disclosed
Brand-name
Compounded only

The scorecard

Lyfe Rx scored on our six published factors. See the methodology.

Real-world results70/100
Price honesty74/100
Prescriber access39/100
Formulary choice82/100
Cancellation fairness56/100
Member support70/100

What we like

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

The caveats

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued a warning letter to Lyfe Rx in September 2025; it is public in FDA's warning-letter database

The verdict

Best for: Shoppers who want both compounded molecules from one storefront.

Ranked #279 of 548 providers we have reviewed — for comparison, read the CoreAge Rx review, ranked #1. In the ranking it sits between June Health at #278, 65/100 above and Mint Medical Clinic at #280, 65/100 below, with the OrderlyMeds write-up the next one down.

If that review leaves you undecided, the 7 programs we rank against Lyfe Rx are graded on the same six factors and listed in score order. For the wider picture, every review we have published ranks the field on the same six factors. We have also compared it head to head: CoreAge Rx vs Lyfe Rx goes to CoreAge Rx, 94/100 to 65/100.

Compare with other providers

The closest reviews to Lyfe Rx by Verdict Score — the realistic shortlist if you are weighing this one up.

Pricing, states and verification reflect Lyfe Rx's public disclosures at last review; the Verdict Score is our editorial judgment per the methodology. Prices change — confirm on Lyfe Rx's site. Not medical advice; see our disclosure.

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