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Ranked #261 · Grade C

Onyx Weight Loss review

Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.

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Semaglutide
From $228/mo (starting dose, compounded)
Tirzepatide
From $280/mo (starting dose, compounded)
Coverage
8 states
Brand-name
Compounded only

The scorecard

Onyx Weight Loss scored on our six published factors. See the methodology.

Real-world results65/100
Price honesty64/100
Prescriber access47/100
Formulary choice82/100
Cancellation fairness56/100
Member support74/100

What we like

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

The caveats

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

The verdict

Best for: Shoppers who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.

Ranked #261 of 499 providers we have reviewed — for comparison, read what CoreAge Rx scores, and why, our #1 pick. On the board it sits between OnlyRx, 64/100 above and QuickMD at 64/100 below, with the ReadyRx ruling the next one down.

If that ruling leaves you undecided, the 7 programmes we rank against Onyx Weight Loss are graded on the same six factors and listed in score order. We have also ruled on it directly: CoreAge Rx vs Onyx Weight Loss goes to CoreAge Rx, 94/100 to 64/100.

Compare with other providers

All 498 other providers we've reviewed, in our overall ranking order.

Every other program we track (492)

Pricing, states and verification reflect Onyx Weight Loss's public disclosures at last review; the Verdict Score is our editorial judgment per the methodology. Prices change — confirm on Onyx Weight Loss's site. Not medical advice; see our disclosure.

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