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The GLP-1 Verdict
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Ranked #409 · Grade C

1st Optimal review

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.

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Semaglutide
Not disclosed
Tirzepatide
Not disclosed
Coverage
Not disclosed
Brand-name
Compounded only

The scorecard

1st Optimal scored on our six published factors. See the methodology.

Real-world results64/100
Price honesty20/100
Prescriber access54/100
Formulary choice46/100
Cancellation fairness92/100
Member support74/100

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

The caveats

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

The verdict

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program. 1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets.

Ranked #409 of 539 providers we have reviewed — for comparison, read the CoreAge Rx review, our #1 pick. In the ranking it sits between KERNX Health at #408, 56/100 above and Always Wellness and Recovery at #410, 56/100 below, with the AVArx ruling the next one down.

If that ruling leaves you undecided, the 7 programs we rank against 1st Optimal are graded on the same six factors and listed in score order.If you would rather start from the top of the field, what GLP-1s cost without insurance is the place to start if you are still shortlisting. We have also ruled on it directly: CoreAge Rx vs 1st Optimal goes to CoreAge Rx, 94/100 to 56/100.

Compare with other providers

The closest rulings to 1st Optimal by Verdict Score — the realistic shortlist if you are weighing this one up.

Browse all 539 rulings, ranked →

Pricing, states and verification reflect 1st Optimal's public disclosures at last review; the Verdict Score is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.

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